Formulation & Drug Delivery

The Impact of Nanotechnology in Drug Delivery: Global Developments, Market Analysis, and Future Prospects

This report by NanoMarkets, LC includes an overview of nanoenabled drug delivery technologies, commercial applications and information on the companies pursuing them, information on nanotechnology initiatives and regulation in major international markets (North America, EU, Japan, Israel, etc.), as well as eight-year worldwide forecasts on the industry's anticipated growth and timing thereof.
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Felix Franks on Critical-to-Quality Process Parameters for Lyophilization

The inventor of the stabilization process used to formulate Exubera has found that mentioning the glassy state has often produced a similar effect in his pharma listeners. Due to lack of interdisciplinary understanding, he says, freeze drying is still "hit or miss" at many pharmaceutical companies. In Chapter 3 of his best-selling book, he outlines product and process parameters.
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Next Generation Nanosuspension Processing for the Delivery of Non-Soluble Drugs

Roughly half of all new drugs in development are poorly soluble and often associated with low bioavailability. Among the most promising solutions to this challenge are nanosuspensions, defined as a colloidal dispersion of submicron pure drug particles that are stabilized by surfactants. The small particle size provides increased surface area which can significantly improve bioavailability.
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